Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic Pathway
نویسندگان
چکیده
منابع مشابه
Seneca Valley Virus
Cleaning and Disinfecting The efficacy of most disinfectants against SVV is not clearly known. Because vesicular diseases are clinically indistinguishable, disinfection protocols for FMDV should be followed even if SVV is suspected. This includes use of: sodium hydroxide, sodium carbonate, 0.2% citric acid, aldehydes, and oxidizing disinfectants including sodium hypochlorite. Below are EP...
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In the Materials and Methods section, there is an error in the equation in the section titled " In Vitro Cleavage Assay. " Please view the complete, correction equation: Copyright: © 2015 Miles et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the o...
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The oncolytic picornavirus Seneca Valley Virus (SVV-001) demonstrates anti-tumor activity in models of small cell lung cancer (SCLC), but may ultimately need to be combined with cytotoxic therapies to improve responses observed in patients. Combining SVV-001 virotherapy with a peptide prodrug activated by the viral protease 3Cpro is a novel strategy that may increase the therapeutic potential o...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2019
ISSN: 1664-302X
DOI: 10.3389/fmicb.2019.01202